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Seleno-L-methionine has been used: in toxicity studies in Japanese Medaka embryosto study its effects on selenium status indicators in pregnant long-tailed macaques (Macaca Fascicularis)to label proteins for single wavelength anomalous dispersion (SAD) phasing
methyllithium
α-amino-γ-bromobutyric acid methyl ester hydrochloride
Seleno-L-methionine
| Conditions | Yield |
|---|---|
|
methyllithium; α-amino-γ-bromobutyric acid methyl ester hydrochloride;
With
selenium; boric acid tributyl ester;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
at -78 - 20 ℃;
for 0.166667h;
Inert atmosphere;
With
methanol; sodium hydroxide;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
for 0.166667h;
Temperature;
Reagent/catalyst;
|
66% |
dimethyl sulfate
L,L-selenohomocystine
Seleno-L-methionine
| Conditions | Yield |
|---|---|
|
L,L-selenohomocystine;
With
sodium tetrahydroborate; ethanol;
at 30 - 45 ℃;
for 5h;
Inert atmosphere;
dimethyl sulfate;
at 25 - 30 ℃;
for 3h;
Temperature;
|
81.8% |
The CAS number of L-(+)-Selenomethionine is 3211-76-5.
More information of L-(+)-Selenomethionine 3211-76-5 are:
|
CAS Number |
3211-76-5 |
|
Melting Point |
265 °C |
|
Boiling Point |
320.78 °C at 760 mmHg |
|
Flash Point |
147.803 °C |
|
Refractive Index |
18 ° (C=0.5, 2mol/L HCl) |
|
HS CODE |
29309090 |
|
PSA |
63.32000 |
|
LogP |
0.65930 |
|
Pka |
2.26±0.10(Predicted) |
Synonyms for L-(+)-Selenomethionine 3211-76-5:Butanoic acid,2-amino-4-(methylseleno)-, (S)-;Butyric acid, 2-amino-4-(methylselenyl)-, L-(8CI);L-Selenomethionine;Seleno-L-methionine;Selenomethionine;
The chemical formula of L-(+)-Selenomethionine is C5H11NO2Se which containing 5 Carbon atoms,11 Hydrogen atoms,1 Nitrogen atoms,2 Oxygen atoms and 1 Selenium atoms,and the molecular weight of L-(+)-Selenomethionine is 196.108.
L-(+)-Selenomethionine, also known as Seleno-L-Methionine (SeMet), is an organic form of selenium found in Cupriavidus metallidurans. It is the L-enantiomer of selenomethionine and exists as a solid with unique chemical properties. L-(+)-Selenomethionine has been shown to increase the expression of glutathione peroxidase, which is an essential antioxidant enzyme in the body.
InChI:InChI=1/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
Relevant articles related to L-(+)-Selenomethionine:
|
Article |
Source |
|
Synthetic method of L-selenomethionine |
- Paragraph 0026-0039, (2020/02/17) |
|
Preparation method of L-selenomethionine |
- Paragraph 0030-0040, (2020/01/12) |
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