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S-Adenosylmethionine

  • CasNo.:17176-17-9
  • Purity:
  • Content:
  • MF:C15H22N6O5S
  • Packing:
  • MW:398.443
  • Apply:
Inquiry

Manufacturer supply S-Adenosylmethionine 17176-17-9 with sufficient stock and high standard

  • Molecular Formula:C15H22N6O5S
  • Molecular Weight:398.443
  • Melting Point:78℃ 
  • PSA:273.51000 
  • LogP:1.33920 

S-ADENOSYL-L-METHIONINE(Cas 17176-17-9) Usage

Biological Activity

S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine.

InChI:InChI=1/C15H22N6O5S.C7H8O3S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);2-5H,1H3,(H,8,9,10)/t7-,8+,10+,11+,14+,27?;/m0./s1

17176-17-9 Relevant articles

Thermostable enzyme-immobilized magnetic responsive Ni-based metal-organic framework nanorods as recyclable biocatalysts for efficient biosynthesis of: S -adenosylmethionine

He, Jie,Sun, Shanshan,Zhou, Zhao,Yuan, Qipeng,Liu, Yanhui,Liang, Hao

supporting information, p. 2077 - 2085 (2019/02/12)

A novel magnetic responsive Ni-based met...

Mechanism of a Class C Radical S-Adenosyl- l -methionine Thiazole Methyl Transferase

Zhang, Zhengan,Mahanta, Nilkamal,Hudson, Graham A.,Mitchell, Douglas A.,Van Der Donk, Wilfred A.

, p. 18623 - 18631 (2017/12/26)

The past decade has seen the discovery o...

Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-L-methionine analogues

Singh, Shanteri,Zhang, Jianjun,Huber, Tyler D.,Sunkara, Manjula,Hurley, Katherine,Goff, Randal D.,Wang, Guojun,Zhang, Wen,Liu, Chunming,Rohr, Juergen,Van Lanen, Steven G.,Morris, Andrew J.,Thorson, Jon S.

supporting information, p. 3965 - 3969 (2014/05/06)

A chemoenzymatic platform for the synthe...

Chemical Synthesis Of S-Adenosyl-L-Methionine With Enrichment Of (S,S)-Isomer

-

Page/Page column 4; 5, (2008/06/13)

This invention relates to an improved pr...

17176-17-9 Process route

L-methionine
63-68-3,26062-47-5,58576-49-1

L-methionine

ATP
56-65-5,896506-78-8

ATP

S-Adenosyl-L-methionine
14031-35-7,17176-17-9,29908-03-0,75044-81-4,78548-84-2,79647-17-9,91279-78-6

S-Adenosyl-L-methionine

5'-Deoxy-5'-methylthioadenosine
2457-80-9

5'-Deoxy-5'-methylthioadenosine

Conditions
Conditions Yield
With recombinant Methanocaldococcus jannaschii methionine adenosyltransferase; potassium chloride; magnesium chloride; In aq. buffer; at 65 ℃; for 4h; pH=8; Temperature; Reagent/catalyst; Enzymatic reaction;
1-methylhexahydropyrylium tetrafluoroborate
6914-65-4

1-methylhexahydropyrylium tetrafluoroborate

S-(5'-adenosyl)-L-homocysteine
979-92-0

S-(5'-adenosyl)-L-homocysteine

S-Adenosyl-L-methionine
14031-35-7,17176-17-9,29908-03-0,75044-81-4,78548-84-2,79647-17-9,91279-78-6

S-Adenosyl-L-methionine

Conditions
Conditions Yield
1-methylhexahydropyrylium tetrafluoroborate; S-(5'-adenosyl)-L-homocysteine; With sulfuric acid; trifluoroacetic acid; at 0 ℃;
In dichloromethane; water; Product distribution / selectivity;

17176-17-9 Upstream products

  • 74-88-4
    74-88-4

    methyl iodide

  • 979-92-0
    979-92-0

    S-(5'-adenosyl)-L-homocysteine

  • 2280-44-6
    2280-44-6

    D-Glucose

  • 63-68-3
    63-68-3

    L-methionine

17176-17-9 Downstream products

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    2182-14-1

    vindoline

  • 94419-25-7
    94419-25-7

    N-Methylnicotinium

  • 60282-15-7
    60282-15-7

    R-(+)-N'-methylnicotinium ion

  • 94419-25-7
    94419-25-7

    R-(+)-N-methylnicotinium ion

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