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Berberine hydrochloride is an isoquinoline alkaloid derived from various plant sources, such as barberry, goldenseal, and Oregon grape. It exhibits a wide range of pharmacological properties, including antiarrhythmic, alpha2 agonist, anticonvulsant, anti-inflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, and immunostimulant activities. Berberine hydrochloride has gained attention for its potential chemopreventive properties and its ability to inhibit the enzyme cyclooxygenase-2 (COX-2) and Activator Protein 1 (AP-1), which play critical roles in inflammation and carcinogenesis.
An ingredient in some commercial eyewash products.
The CAS number of Berberine hydrochloride is 633-65-8.
More information of Berberine hydrochloride 633-65-8 are:
|
CAS Number |
633-65-8 |
|
Density |
1.654g/cm3 |
|
Melting Point |
204-206 °C (dec.) |
|
HS CODE |
29349990 |
|
PSA |
40.80000 |
|
LogP |
0.10030 |
The chemical formula of Berberine hydrochloride is C20H18NO4.Cl which containing 20 Carbon atoms,18 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 1 Chlorine atoms,and the molecular weight, and the molecular weight of Berberine hydrochloride is 371.82
Berberine hydrochloride is an isoquinoline alkaloid derived from various plant sources, such as barberry, goldenseal, and Oregon grape. It exhibits a wide range of pharmacological properties, including antiarrhythmic, alpha2 agonist, anticonvulsant, anti-inflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, and immunostimulant activities. Berberine hydrochloride has gained attention for its potential chemopreventive properties and its ability to inhibit the enzyme cyclooxygenase-2 (COX-2) and Activator Protein 1 (AP-1), which play critical roles in inflammation and carcinogenesis.
InChI:InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;
Relevant articles related to Berberine hydrochloride:
|
Article |
Source |
|
Thermodynamic study on the effects of β-cyclodextrin inclusion with berberine |
Yu,Wei,Gao,Zhao , p. 249 - 256 (2002) |
|
A synthetic preparation method for small carbags hydrochloric acid |
- , (2021/12/08) |
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