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2-Deoxy-D-Glucose

  • CasNo.:154-17-6
  • Purity:
  • Content:
  • MF:C6H12O5
  • Packing:
  • MW:164.158
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Manufacturer supply good quality 2-Deoxy-D-Glucose 154-17-6 with stock We supply high quality 2-Deoxy-D-glucose (CAS 154-17-6), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the 2-Deoxy-D-glucose ?

2-Deoxy-D-glucose is white to light yellow crystal powder, while it's Molecular Formula is C6H12O5. 2-Deoxy-D-glucose (2-DG) is used in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). 2-Deoxy-D-glucose is used in the development of anti-cancer strategies that involve radio- and chemosensitization and oxidative stress.

What is the CAS number for 2-Deoxy-D-glucose ?

The CAS number of 2-Deoxy-D-glucose is 154-17-6.

More information of 2-Deoxy-D-glucose 154-17-6 are:

Synonyms

D-Glucose, 2-deoxy-;Deoxyglucose;2-DG;2-Deoxy-D-arabino-hexose;

CAS Number

154-17-6

Molecular Formula

C6H12O5

Molecular Weight

164.158

Density

1.533 g/cm3

Melting Point

146-147 °C(lit.)

Boiling Point

411 °C at 760 mmHg

Flash Point

202.3 °C

HS CODE

29400090

PSA

97.99000

LogP

-2.34960

Pka

pK1:12.52 (25°C)

What is 2-Deoxy-D-glucose (154-17-6) used for?

2-Deoxy-D-glucose (154-17-6) is a synthetic glucose analog with extensive biological effects. It is commonly thought of as an inhibitor of glycolysis, but its metabolic effects are wide-ranging. 2-Deoxy-D-glucose competitively inhibits glucose uptake via its metabolite 2-Deoxy-D-glucose-6-phosphate, which inhibits hexokinase and phosphoglucose-isomerase leading to decreased ATP production, cell cycle blockage, decreased cell growth and ultimately cell death.1,2

InChI:InChI=1/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2/t3-,4-,5-,6+/m1/s1

Articles related to 2-Deoxy-D-glucose:

Article

Source

SYNTHESIS OF 2-DEOXY-D-arabino-HEXITOL AND ITS OXIDATION TO 5-DEOXY-D-threo-HEXULOSE ("5-DEOXY-D-FRUCTOSE") USING IMMOBILIZED CELLS OF Gluconobacter oxydans

Tiwari, Kamal N.,Dhawale, Motiram R.,Szarek, Walter A.,Hay, George W.,Kropinski, Andrew M. B.

, p. 19 - 24 (1986)

-

Bolliger

, p. 989 (1951)

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