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Manufacturer supply good quality 2-Deoxy-D-Glucose 154-17-6 with stock We supply high quality 2-Deoxy-D-glucose (CAS 154-17-6), in stock, factory directly supply to clients, lower prices, more competitiveness.
2-Deoxy-D-glucose is white to light yellow crystal powder, while it's Molecular Formula is C6H12O5. 2-Deoxy-D-glucose (2-DG) is used in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). 2-Deoxy-D-glucose is used in the development of anti-cancer strategies that involve radio- and chemosensitization and oxidative stress.
The CAS number of 2-Deoxy-D-glucose is 154-17-6.
More information of 2-Deoxy-D-glucose 154-17-6 are:
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Synonyms |
D-Glucose, 2-deoxy-;Deoxyglucose;2-DG;2-Deoxy-D-arabino-hexose; |
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CAS Number |
154-17-6 |
|
Molecular Formula |
C6H12O5 |
|
Molecular Weight |
164.158 |
|
Density |
1.533 g/cm3 |
|
Melting Point |
146-147 °C(lit.) |
|
Boiling Point |
411 °C at 760 mmHg |
|
Flash Point |
202.3 °C |
|
HS CODE |
29400090 |
|
PSA |
97.99000 |
|
LogP |
-2.34960 |
|
Pka |
pK1:12.52 (25°C) |
2-Deoxy-D-glucose (154-17-6) is a synthetic glucose analog with extensive biological effects. It is commonly thought of as an inhibitor of glycolysis, but its metabolic effects are wide-ranging. 2-Deoxy-D-glucose competitively inhibits glucose uptake via its metabolite 2-Deoxy-D-glucose-6-phosphate, which inhibits hexokinase and phosphoglucose-isomerase leading to decreased ATP production, cell cycle blockage, decreased cell growth and ultimately cell death.1,2
InChI:InChI=1/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2/t3-,4-,5-,6+/m1/s1
Articles related to 2-Deoxy-D-glucose:
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Article |
Source |
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SYNTHESIS OF 2-DEOXY-D-arabino-HEXITOL AND ITS OXIDATION TO 5-DEOXY-D-threo-HEXULOSE ("5-DEOXY-D-FRUCTOSE") USING IMMOBILIZED CELLS OF Gluconobacter oxydans |
Tiwari, Kamal N.,Dhawale, Motiram R.,Szarek, Walter A.,Hay, George W.,Kropinski, Andrew M. B. , p. 19 - 24 (1986) |
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Bolliger , p. 989 (1951) |
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