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Eicosapentaenoic Acid

  • CasNo.:10417-94-4
  • Purity:
  • Content:
  • MF:C20H30O2
  • Packing:
  • MW:302.457
  • Apply:
Inquiry

Manufacturer supply high quality Eicosapentaenoic Acid 10417-94-4 with GMP standards

  • Molecular Formula:C20H30O2
  • Molecular Weight:302.457
  • Appearance/Colour:Smell slightly yellow transparent 
  • Vapor Pressure:6.04E-09mmHg at 25°C 
  • Melting Point:-54--53 °C(lit.) 
  • Refractive Index:n20/D 1.4977(lit.)  
  • Boiling Point:439.3 °C at 760 mmHg 
  • PKA:4.75±0.10(Predicted) 
  • Flash Point:336 °C 
  • PSA:37.30000 
  • Density:0.941 g/cm3  
  • LogP:5.99270 

Icosapent(Cas 10417-94-4) Usage

Biochem/physiol Actions

5-Lipoxygenase inhibitor; reduces thromboxane A2 production.

Definition

ChEBI: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.

Brand name

Decabid (Lilly).

General Description

Eicosapentaenoic acid (cis-5,8,11,14,17), also known as EPA, is a long-chain omega-3 fatty acid. Studies suggests that EPA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders. This certified solution standard is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in mass spectrometry-based EPA testing applications such as assessment of cardiovascular?disease risk and fatty acid deficiency, and detection and quantification of EPA in nutraceuticals and dietary supplements.

InChI:InChI=1/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-

10417-94-4 Relevant articles

Apoptosis-inducing galactolipids from a cultured marine diatom, Phaeodactylum tricornutum

Andrianasolo, Eric H.,Haramaty, Liti,Vardi, Assaf,White, Eileen,Lutz, Richard,Falkowski, Paul

, p. 1197 - 1201 (2008)

Two monogalactosyl diacylglycerols, 1 an...

Enzymatic synthesis of 1,3-dicapryloyl-2-eicosapentaenoylglycerol

Irimescu, Roxana,Yasui, Mamoru,Iwasaki, Yugo,Shimidzu, Nobuyoshi,Yamane, Tsuneo

, p. 501 - 506 (2000)

1,3-Dicapryloyl-2-eicosapentaenoylglycer...

A simple preparation of 17(R)-hydroxyeicosatetraenoic and eicosapentaenoic acids from the eicosanoylphloroglucinols, components of the brown alga, Zonaria diesingiana

Munakata, Tatsuo,Ooi, Takashi,Kusumi, Takenori

, p. 249 - 250 (1997)

The alkaline treatment of 17(R)-hydroxye...

Antioxidative Properties and Chemical Changes of Quercetin in Fish Oil: Quercetin Reacts with Free Fatty Acids to Form Its Ester Derivatives

Liu, Shaojun,Zhu, Yamin,Liu, Ning,Fan, Daming,Wang, Mingfu,Zhao, Yueliang

, p. 1057 - 1067 (2021)

In this research, we studied the antioxi...

Chemoenzymatic synthesis of symmetrically structured triacylglycerols possessing short-chain fatty acids

Magnusson, Carlos D.,Haraldsson, Gudmundur G.

, p. 2728 - 2731 (2010)

Synthesis of symmetrically structured tr...

Chemoenzymatic synthesis of structured triacylglycerols containing eicosapentaenoic and docosahexaenoic acids

Haraldsson, Gudmundur G.,Halldorsson, Arnar,Kulas, Elin

, p. 1139 - 1145 (2000)

There are indications in the recent lite...

An allelopathic polyunsaturated fatty acid from red algae

Suzuki, Minoru,Wakana, Isamu,Denboh, Takashi,Tatewaki, Masakazu

, p. 63 - 65 (1996)

An allelopathic substance, which display...

Chemoenzymatic synthesis of a focused library of enantiopure structured 1-O-alkyl-2,3-diacyl-sn-glycerol type ether lipids

Magnusson, Carlos D.,Gudmundsdottir, Anna V.,Haraldsson, Gudmundur G.

, p. 1821 - 1836 (2011)

A highly efficient two-step chemoenzymat...

Lyophilized extracts from vegetable flours as valuable alternatives to purified oxygenases for the synthesis of oxylipins

Sanfilippo, Claudia,Paterna, Angela,Biondi, Daniela M.,Patti, Angela

, (2019/10/05)

In this work, the whole aqueous extracts...

COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME

-

Paragraph 00130; 00132, (2018/03/06)

The disclosures herein provide compounds...

ENTERAL FEEDING DEVICE

-

, (2018/10/21)

The present invention relates to a fluid...

10417-94-4 Process route

all-(Z)-ethyl 4,7,10,13,16,19-docosahexaenoate
81926-94-5,84494-72-4

all-(Z)-ethyl 4,7,10,13,16,19-docosahexaenoate

eicosapentaenoic acid ethyl ester
86227-47-6,84494-70-2

eicosapentaenoic acid ethyl ester

all cis-5,8,11,14,17-eicosapentaenoic acid
10417-94-4

all cis-5,8,11,14,17-eicosapentaenoic acid

docosahexaenoic acid
6217-54-5

docosahexaenoic acid

Conditions
Conditions Yield
all-(Z)-ethyl 4,7,10,13,16,19-docosahexaenoate; eicosapentaenoic acid ethyl ester; With water; sodium hydroxide; In methanol; at 20 ℃; for 1.5h;
With hydrogenchloride; In water; Cooling with ice;
eicosapentaenoic acid ethyl ester
86227-47-6,84494-70-2

eicosapentaenoic acid ethyl ester

all cis-5,8,11,14,17-eicosapentaenoic acid
10417-94-4

all cis-5,8,11,14,17-eicosapentaenoic acid

Conditions
Conditions Yield
With ethylenediaminetetraacetic acid; edetate disodium; In ethanol; water; at 60 - 65 ℃; for 2h;
98%
With immobilized lipase from Candida Antarctica; water; In 1,4-dioxane; at 55 ℃; for 3h; Enzymatic reaction;
98%
With Candida antarctica lipase; water; at 40 ℃;
97.6%
With sodium hydroxide; edetate disodium; In ethanol; at 65 ℃;
97%
eicosapentaenoic acid ethyl ester; With water; sodium hydroxide; In methanol; at 20 ℃; for 1.5h;
With hydrogenchloride; In methanol; water; Cooling with ice;
96%
With sodium hydroxide; In ethanol; water; at 20 ℃; for 2h;
90%
With sodium hydroxide; In ethanol; water; at 20 ℃; for 2h;
90%
With water; sodium hydroxide; In methanol; at 20 ℃; for 4h; Concentration;
87.4%
With sodium hydroxide; In methanol; water; at 20 ℃; for 2h;
83.12%
With water; sodium hydroxide; In methanol; at 20 ℃; for 2h;
83.12%
With methanol; water; sodium hydroxide; at 20 ℃; for 2h;
83.12%
With lithium hydroxide; In ethanol; water; Ambient temperature;
With water;
In water;
With potassium hydroxide; In ethanol; water; at 62 ℃; for 1h; Inert atmosphere;

10417-94-4 Upstream products

  • 2734-47-6
    2734-47-6

    (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-icosapentaenoic acid methyl ester

  • 121245-05-4
    121245-05-4

    (2S)-1-O-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-2-O-(6Z,9Z,12Z,15Z-octadecatetranoyl)-3-β-D-galactopyranosyl-sn-glycerol

  • 86227-47-6
    86227-47-6

    eicosapentaenoic acid ethyl ester

  • 5871-07-8
    5871-07-8

    5,8,11,14,17-eicosapentaynoic acid

10417-94-4 Downstream products

  • 33156-92-2
    33156-92-2

    Ectocarpen

  • 99660-94-3
    99660-94-3

    triglyceride of eicosapentaenoic acid

  • 140670-39-9
    140670-39-9

    (5Z,8Z,11Z,14Z,17Z)-2,3-dihydroxypropyl eicosa-5,8,11,14,17-pentaenoate

  • 140670-41-3
    140670-41-3

    1,3-dieicosapentaenoylglycerol

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