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4-Hydroxyisoleucine

  • CasNo.:55399-93-4
  • Purity:
  • Content:
  • MF:C6H13NO3
  • Packing:
  • MW:147.174
  • Apply:
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Factory Sells Best Quality 4-Hydroxyisoleucine 55399-93-4 with USP

  • Molecular Formula:C6H13NO3
  • Molecular Weight:147.174
  • Vapor Pressure:1.11E-05mmHg at 25°C 
  • Melting Point:223-224℃ 
  • Refractive Index:1.495 
  • Boiling Point:331.6ºCat 760 mmHg 
  • PKA:2.41±0.25(Predicted) 
  • Flash Point:154.4ºC 
  • PSA:83.55000 
  • Density:1.181 g/cm3 
  • LogP:0.11550 

4-Hydroxyisoleucine(Cas 55399-93-4) Usage

Definition

ChEBI: An L-isoleucine derivative that is L-isoleucine bearing a (4S)-hydroxy substituent.

InChI:InChI=1/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)

55399-93-4 Relevant articles

Engineering Bacillus subtilis Isoleucine Dioxygenase for Efficient Synthesis of (2 S,3 R,4 S)-4-Hydroxyisoleucine

Du, Ping,Pan, Jiang,Qian, Xiao-Long,Xu, Jian-He,Yan, Shuai,Yu, Hui-Lei,Zhang, Zhi-Jun

, p. 14555 - 14563 (2020/12/22)

Isoleucine dioxygenase (IDO)-catalyzed h...

Repurposing Nonheme Iron Hydroxylases to Enable Catalytic Nitrile Installation through an Azido Group Assistance

Davidson, Madison,McNamee, Meredith,Fan, Ruixi,Guo, Yisong,Chang, Wei-Chen

supporting information, p. 3419 - 3423 (2019/03/07)

Three mononuclear nonheme iron and 2-oxo...

Attempt to simultaneously generate three chiral centers in 4-hydroxyisoleucine with microbial carbonyl reductases

Hibi, Makoto,Takahashi, Koji,Kako, Junko,Wakita, Yuuta,Kodera, Tomohiro,Shimizu, Sakayu,Yokozeki, Kenzo,Ogawa, Jun

, p. 1327 - 1332 (2017/10/05)

A panel of microorganisms was screened f...

A practical and efficient total synthesis of potent insulinotropic (2S,3R,4S)-4-Hydroxyisoleucine through a chiral N-protected γ-keto- α-aminoester

De Lamo Marin, Sandra,Catala, Cedric,Kumar, Sreekantha Ratna,Valleix, Alain,Wagner, Alain,Mioskowski, Charles

experimental part, p. 3985 - 3989 (2010/09/18)

(2S,3R,4S)-4-Hydroxyisoleucine, which ex...

55399-93-4 Process route

(3S,4R,5S)-3-amino-4,5-dimethyldihydrofuran-2(3H)-one
55527-86-1,168610-73-9,681230-42-2,695148-12-0,697797-11-8

(3S,4R,5S)-3-amino-4,5-dimethyldihydrofuran-2(3H)-one

(3S,4R,5R)-3-Amino-4,5-dimethyl-dihydro-furan-2-one
55527-85-0,168610-73-9,681230-42-2,695148-12-0,697797-11-8

(3S,4R,5R)-3-Amino-4,5-dimethyl-dihydro-furan-2-one

(2S,3R,4S)-4-hydroxyisoleucine
55399-93-4,21704-86-9

(2S,3R,4S)-4-hydroxyisoleucine

Conditions
Conditions Yield
(3S,4R,5S)-3-amino-4,5-dimethyldihydrofuran-2(3H)-one; (3S,4R,5R)-3-Amino-4,5-dimethyl-dihydro-furan-2-one; With lithium hydroxide; water; at 20 ℃; for 2h;
With acetic acid;
98%
With lithium hydroxide; water; at 20 ℃; for 2h;
80%
4-hydroxyisoleucine γ-lactone
168610-73-9,681230-42-2,695148-12-0,697797-11-8

4-hydroxyisoleucine γ-lactone

(2S,3R,4S)-4-hydroxyisoleucine
55399-93-4,21704-86-9

(2S,3R,4S)-4-hydroxyisoleucine

Conditions
Conditions Yield
4-hydroxyisoleucine γ-lactone; With lithium hydroxide; water; at 20 ℃; for 2h;
With acetic acid; In water;

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